Bode Group Publications
Mitchell, T. A.; Bode, J. W. "Synthesis of Dialkyl Ethers from Organotrifluoroborates and Acetal", J. Am. Chem. Soc. 2009, 131,18057–18059. Link
Chiang, P.-C.; Kim, Y.; Bode, J. W. "Catalytic Amide Formation with α'-Hydroxyenones as Acylating Reagents", Chem. Commun., 2009, 4566–4568. Link
Chiang, P.-C.; Rommel, M.; Bode, J. W. "α'-Hydroxyenones as Mechanistic Probes and Scope-Expanding Surrogates for α,β-Unsaturated Aldehydes in N-Heterocyclic Carbene-Catalyzed Reactions", J. Am. Chem. Soc. 2009, 131, 8714–8718. Link
Struble, J. R.; Bode, J. W. "Formal Synthesis of Salinosporamide A via NHC-catalyzed Intramolecular Lactonization", Tetrahedron, 2009, 65, 4957–4967. Link
Ju, L.; Bode, J. W. "A general strategy for the preparation of C-terminal peptide a-ketoacids by solid phase peptide synthesis", Org. Biomol. Chem. 2009, 7, 2259–2264. Link
Fukuzumi, T.; Bode, J. W. "A Reagent for the Convenient, Solid-Phase Synthesis of N-Terminal Peptide Hydroxylamines for Chemoselective Ligations" J. Am. Chem. Soc. 2009, 131, 3864–3865. Link
Lippert, A. R.; Keleshian, V. L.; Bode, J. W. "Dynamic supramolecular complexation by shapeshifting organic molecules" Org. Biomol. Chem. 2009, 7, 1529–1532. Link
Ishida, H.; Carrillo, N.; Bode, J. W. "Synthesis of an enantiopure isoxazolidine monomer for b3-aspartic acid in chemoselective β-oligopeptide synthesis" Tetrahedron Lett. 2009, 50, 3258–3260. Link
Kaeobamrung, J.; Bode, J. W. "Stereodivergency of Triazolium and Imidazolium-Derived NHCs for Catalytic, Enantioselective Cyclopentane Synthesis" Org. Lett. 2009, 11, 677–680. Link
Rommel, M.; Fukuzumi, T.; Bode, J. W. "Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings", J. Am. Chem. Soc. 2008, 130, 17266–17267. Link
He, M.; Beahm, B. J.; Bode, J. W. "Chiral NHC-Catalyzed Oxodiene Diels−Alder Reactions with alpha-Chloroaldehyde Bisulfite Salts", Org. Lett. 2008, 10, 3817–3820. Link
Struble, J. R.; Bode, J. W. "A modular synthesis of chiral aminoindanol-derived imidazolium salts", Tetrahedron 2008, 64, 6961–6972. Link
Ju, L.; Lippert, A. R.; Bode, J. W. "Stereoretentive Synthesis and Chemoselective Amide-Forming Ligations of C-Terminal Peptide alpha-Ketoacids", J. Am. Chem. Soc. 2008, 130, 4253–4255. Link
Struble, J.R.; Kaeobamrung, J.; Bode, J.W. "Synthesis of an N-Mesityl Substituted Chiral Imidazolium Salt for NHC-Catalyzed Reactions", Org. Lett. 2008, 10, 957–960. Link
He, M.; Bode, J. W. "Enantioselective, NHC-Catalyzed Bicyclo-beta-Lactam Formation via Direct Annulations of Enals and Unsaturated N-Sulfonyl Ketimines", J. Am. Chem. Soc. 2008, 130, 418–419. Link
Bode, J. W.; Sohn, S. S. "N-Heterocyclic Carbene-Catalyzed Redox Amidations of alpha-Functionalized Aldehydes with Amines", J. Am. Chem. Soc. 2007, 129, 13798–13799. Link
Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. "Enantioselective, Cyclopentene-Forming Annulations via NHC-Catalyzed Benzoin–Oxy-Cope Reactions", J. Am. Chem. Soc. 2007, 129, 3520–3521. Link
He, M.; Uc, G. J.; Bode, J. W. "Chiral, N-Heterocyclic Carbene Catalyzed Oxodiene Diels-Alder Reactions with Low Catalyst Loadings", J. Am. Chem. Soc. 2006, 128, 15088–15089. Link
Bode, J. W. "Emerging Methods for the Synthesis of Amide and Peptide Bonds", Curr. Opin. Drug Discov. Devel. 2006, 9, 765–775. PubMed
Lippert, A. R.; Kaeobamrung, J.; Bode, J. W. "Synthesis of Oligosubstituted Bullvalones: Shapeshifiting Molecules Under Basic Conditions ", J. Am. Chem. Soc. 2006, 128, 14738–14739. Link
Sohn, S. S.; Bode, J. W. "N-Heterocyclic Carbene Catalyzed C–C Bond Cleavage in Redox Esterifications of Chiral Formylcyclopropanes", Angew. Chem. Int. Ed. 2006, 6021–6024. Link
He, M.; Struble, J. R.; Bode, J. W. "Highly Enantioselective Azadiene Diels-Alder Reactions Catalyzed by Chiral N-Heterocyclic Carbenes", J. Am. Chem. Soc. 2006, 128, 8148–8150. Link
Carrillo, N.; Davalos, E. A.; Russak, J. A.; Bode, J. W. "Iterative, Aqueous Synthesis of b3-oligopeptides without Coupling Reagents ", J. Am. Chem. Soc. 2006, 128, 1452-1453. Link, C&E News
Bode, J. W.; Fox, R. M.; Baucom, K. D. "Decarboxylative Condensations of alpha-Ketoacids and N-Alkylhydroxylamines: A New Amide Ligation Reaction", Angew. Chem. Int. Ed.2006, 45, 1248-1252. Link, C&E News
Sohn, S.; Bode, J. W. "Catalytic Generation of Activated Carboxylates from Enals: A Product Determining Role for the Base ", Org. Lett. 2005, 7, 3873-3876. Link, Organic Chemistry Portal, Angew. Highlight
He, M.; Bode, J. W. "Catalytic Synthesis of gamma-Lactams via Direct Annulations of Enals and N-Sulfonylimines", Org. Lett. 2005, 7, 3131–3134. Link, Angew. Highlight
Sohn, S. S.; Rosen, E. L.; Bode, J. W. "N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: gamma-Butyrolactones by Direct Annulations of Enals and Aldehydes", J. Am. Chem. Soc. 2004, 126, 14370-14371. Link, Angew. Highlight
Chow, K. Y.-K.; Bode, J. W. "Catalytic Generation of Activated Carboxylates: Direct, Stereoselective Synthesis of beta-Hydroxyesters from Epoxyaldehydes" J. Am. Chem. Soc. 2004, 126, 8126-8127. Link, Angew. Highlight
Undergraduate, Graduate, and Postdoctoral Publications
- Suzuki, K.; Takikawa, H.; Hachisu, Y.; Bode, J. W. "Isoxazole-directed pinacol rearrangement: stereocontrolled approach to angular stereogenic centers", Angew. Chem. Int. Ed. 2007, 46, 3252–3254. Link
- Takikawa, H.; Hachisu, Y.; Bode, J. W.; Suzuki, K. " Catalytic, Enantioselective Crossed Aldehyde–Ketone Benzoin Cyclizations”, Angew. Chem. Int. Ed. 2006, 45, 3492–3494. Link
- Hachisu, Y.; Bode, J. W.; Suzuki, K. "Thiazolium Ylide Catalyzed Intramolecular Aldehyde--Ketone Benzoin-Forming Reactions: Substrate Scope" Adv. Syn. Cat. 2004, 1097–1100. Link
- Matsuura, T.; Bode, J. W.; Hachisu, Y.; Suzuki, K. "Molecular Sieve (MS 4A) Promoted Cyclocondensation of Hindered, Aromatic Nitrile Oxides and Cyclic Diketones under Mild Conditions", Synlett 2003, 1746-1748. Link
- Hachisu, Y.; Bode, J. W.; Suzuki, K. "Catalytic Intramolecular Aldehyde-Ketone Benzoin Reactions: A Novel Synthesis of Functionalized Preanthraquinones", J. Am. Chem. Soc. 2003, 125, 8432-8433. Link
- Bode, J. W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. Amine-Promoted Cyclocondensation of Highly Substituted Aromatic Nitrile Oxides with Diketones", Tetrahedron Lett. 2003, 44, 3555-3558. Link
- Bode, J. W.; Suzuki K. "Structural Incongruities of Coleophomone Natural Products: Insights by Total Synthesis of a Semi-Synthetic Derivative" Tetrahedron Lett. 2003, 44, 3559-3563. Link
- Bode, J. W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. "Facile Construction and Divergent Transformation of Polycyclic Isoxazoles: Direct Access to Polyketide Architectures", Org. Lett. 2003, 5, 391-394. Link
- Bode, J. W.; Uekusa, H.; Suzuki, K. "Rearrangement Promoted Cascade Reactions for the Stereoselective Synthesis of Highly Functionalized Polycycles", Org. Lett. 2003, 5, 395-398. Link
- Bode, J. W.; Gauthier, D. R.; Carreira, E. M. "Facile Enantioselective Synthesis of a Key Homoallylic Alcohol Building Block for Polyketide Synthesis: TiF4-BINOL Catalyzed Allylsilylation", J. Chem. Soc. Chem. Comm. 2001, 2560-2561. Link
- Bode, J. W.; Carreira, E. M. "Stereoselective Syntheses of Epothilones A and B via Nitrile Oxide Cycloadditions and Related Studies", J. Org. Chem. 2001, 66, 6410-6424. Link
- Bode, J. W.; Carreira, E. M. "A Mild and Chemoselective Method for the Reduction of Conjugated Isoxazolines to Beta-Hydroxy Ketones", Org. Lett. 2001, 3, 1587-1590. Link
- Bode, J. W.; Fraefel, N.; Muri, D.; Carreira, E. M. "A General Solution to the Modular Synthesis of Polyketide Building Blocks via Kanemasa Hydroxyl-Directed Nitrile Oxide Cycloadditions", Angew. Chem. Int. Ed. 2001, 40, 2082-2085. Link
- Bode, J. W.; Carreira, E. M. "Stereoselective Syntheses of Epothilones A and B via Hydroxyl Directed Nitrile Oxide Cycloadditions", J. Am. Chem. Soc. 2001, 123, 3611-3612. Link
- Muri, D.; Bode, J. W.; Carreira, E.M. "A Novel, General Method for the Synthesis of Nitrile Oxides: Dehydration of O-Silylated Hydroxamic Acids", Org. Lett. 2000, 2, 539-541. Link
- Bode, J. W.; Doyle, M. P.; Protopopova, M. N. Zhou, Q-L. "Intramolecular Regioselective Insertion into Unactivated Carbon-Hydrogen Bonds with Diazoacetates of Primary Alcohols Catalyzed by Chiral Dirhodium(II) Carboxamidates. Highly Enantioselective Total Synthesis of Natural Lignan Lactones." J. Org. Chem. 1996, 61, 9146-9155. Link
- Doyle, M.P.; Protopopova, M.N. Zhou, Q.-L.; Bode, J. W.; Simonsen, S.H.; Lynch, V. "Optimization of Enantiocontrol for Carbon-Hydrogen Insertion with Chiral Dirhodium(II) Carboxamidates. Synthesis of Natural Dibenzylbutyrolactone Lignans from 3-Aryl-1-Propyl Diazoacetates in High Optical Purity." J. Org. Chem. 1995, 60, 6654-6655. Link
Book Chapters
- Bode, J. W.; Carreira, E. M. "Total Synthesis of Macrolides" in The Chemical Synthesis of Natural Products; Hale, K. J., Ed.; Sheffield Academic Press: Sheffield, 2000; pp 40-63.